Delineation of the Germline and Somatic Mutation Interaction Landscape in Triple-Negative and Non-Triple-Negative Breast Cancer

Table 1

List of 30 significantly differentially expressed genes mutated in TNBC and non-TNBC with high somatic mutation events per gene.

Genes	Chromosome position	Adjusted value	TNBC somatic mutation events	Non-TNBC somatic mutation events
COPE	19p13.11		3
ENPP5	6p21.1		3
RBM22	5q33.1		3
AGPAT9	4q21.23		2
ALB	4q13.3		2
ASF1B	19p13.12		2
BMP4	14q22.2		2
C3orf62	3p21.31		2
CALB2	16q22.2		2
CAP1	1p34.2		2
CRIP1	14q32.33		2
FANCF	11p14.3		2
FGD1	Xp11.22		2
FHL3	1p34.3		2
FKBPL	6p21.32		2
GATA3	10p14			99
FOXA1	14q21.1			23
FRMPD4	Xp22.2			21
WNK3	Xp11.22			18
PHKA2	Xp22.13			17
ACACB	12q24.11			16
NRCAM	7q31.1			16
RAB3GAP2	1q41			16
SETX	9q34.13			16
CBLB	3q13.11			15
COL4A6	Xq22.3			15
DOCK3	3p21.2			15
ABCB11	2q31.1			14
CDH8	16q21			14
CNTNAP3B	9p11.2			14

Note: blank cells in the 4^th and 5^th columns indicate that the gene is not mutated in that type of breast cancer.