Downregulation of miR-1826 Indicates a Poor Prognosis for Osteosarcoma Patients and Regulates Tumor Cell Proliferation, Migration, and Invasion

Figure 3

Effect of miR-1826 on OS cell proliferation, migration, and invasion in U2OS and SaOS2 cells. (a, b) The expression of miR-1826 was upregulated by the miR-1826 mimic but was downregulated by the miR-1826 inhibitor. (c, d) The CCK-8 assay indicated that OS cell proliferation was enhanced by the knockdown of miR-1826 but was inhibited by the overexpression of miR-1826. (e–h) Cell migration and invasion abilities measured by Transwell assay were facilitated by the downregulation of miR-1826 but were suppressed by the upregulation of miR-1826. , , .

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