Downregulation of miR-1826 Indicates a Poor Prognosis for Osteosarcoma Patients and Regulates Tumor Cell Proliferation, Migration, and Invasion

Table 2

Cox regression analysis for the patients with OS.

Variables	Univariate analysis			Multivariate analysis
	HR	95% CI	value	HR	95% CI	value
miR-1826	2.721	1.499-4.940	0.001	2.452	1.248-4.373	0.014
Age	1.185	0.686-2.047	0.543	1.258	0.724-2.187	0.416
Gender	1.063	0.621-1.821	0.824	1.007	0.583-1.739	0.979
Tumor size	1.045	0.612-1.785	0.871	1.160	0.669-2.010	0.597
Clinical stage	2.253	1.279-3.971	0.005	2.129	1.106-4.099	0.024
Distant metastasis	2.133	1.159-3.925	0.015	1.829	1.007-3.725	0.046