Streptococcus halichoeri: Comparative Genomics of an Emerging Pathogen

Table 2

Virulence factors found in the core genome of Streptococcus halichoeri.

Group	Virulence factor
Adherence	Putative choline binding protein
	Fibronectin-binding protein
	Fibronectin/fibrinogen-binding protein
	Laminin-binding surface protein
	M-like protein
	Sortase A, LPXTG specific
	Collagen-like surface protein
	Streptococcal lipoprotein rotamase A
Enzyme	Enolase
	Streptodornase D
Manganese uptake	Pneumococcal vaccine antigen A homolog
Protease	C3-degrading proteinase
	Immunoglobulin G-endopeptidase (IdeS)/Mac/secreted immunoglobulin-binding protein (Sib38)
	Serine protease, DegP/HtrA, do-like
	Streptococcal cysteine protease (streptopain)/streptococcal pyrogenic exotoxin B (SpeB)
	Streptokinase
Toxin	C3 family ADP-ribosyltransferase
	CAMP factor
	Hemolysin III
Immune evasion	Multidrug resistance protein
Capsid	Capsule biosynthesis protein capA

These proteins are additional to the known streptococcal virulence factors.