Clinical Evaluation of the Diagnostic Role of MicroRNA-155 in Breast Cancer

Table 8

Biomarker index of miR-155 for breast cancer identification using the ROC curve.

Parameters	AUC	Sensitivity (95% CI)	Specificity (95% CI)	Best cutoff
Control/BC	0.89	77.78% (61.92%-88.28%)	88.89% (74.69%-95.59%)	1.40	<0.0001
Grade	0.75	81.82% (52.30%-96.77%)	72.0% (52.42%-85.72%)	1.71	0.015
Stage	0.60	54.55% (28.01%-78.73%)	80.0% (60.87%-91.14%)	1.90	0.327
T size	0.55	42.86% (15.82%-74.95%)	51.72% (34.43%-68.61%)	1.69	0.857
LNM ()	0.66	52.94% (30.96%-73.83%)	84.21% (62.43%-94.48%)	1.885	0.173
HER2	0.52	33.33% (12.06%-64.58)	92.59% (76.63%-98.68%)	2.30	0.855
PR	0.54	42.11% (23.14%-63.72%)	70.59% (46.87%-86.72%)	1.82	0.668
ER	0.58	75.0% (55.10%-88.00%)	50.0% (25.38%-74.62%)	1.88	0.43
Ki-67	0.50	85.71% (60.06%-97.46%)	31.82% (16.36%-52.68%)	1.94	0.935