Identification and Validation of Inflammatory Response-Related Gene Signatures to Predict the Prognosis of Neuroblastoma

Table 2

The information of 11 EFS-related IRRGs by multivariate Cox regression analysis.

Gene	Coef	HR	95% CI	value
GNAI3	0.406	1.50	1.04-2.17	0.031
PTGER2	0.158	1.17	1.00-1.38	0.057
OPRK1	0.153	1.17	1.00-1.35	0.044
RIPK2	-0.470	0.62	0.47-0.83	0.001
NLRP3	-0.139	0.87	0.77-0.99	0.028
KIF1B	-0.422	0.66	0.47-0.91	0.013
HIF1A	0.309	1.36	1.00-1.84	0.046
ACVR2A	-0.283	0.75	0.54-1.05	0.097
ATP2B1	0.318	1.37	1.05-1.80	0.021
LPAR1	-0.379	0.68	0.57-0.82	<0.001
GABBR1	-0.274	0.76	0.60-0.97	0.024

EFS: event-free survival; IRRG: inflammatory response-related gene; HR: hazard ratio; CI: confidence interval.