Identification and Validation of Inflammatory Response-Related Gene Signatures to Predict the Prognosis of Neuroblastoma

Table 3

Univariate Cox regression analyses for identifying prognostic clinical characteristics.

	Univariate analysis (OS)			Univariate analysis (EFS)
	HR	95% CI	value	HR	95% CI	value
Risk score	1.08	1.07-1.10	<0.001	1.23	1.20-1.28	<0.001
Sex	0.81	0.55-1.19	0.288	0.90	0.67-1.21	0.492
Age	1.0003	1.0002-1.0004	<0.001	1.0003	1.0002-1.0004	<0.001
MYCN status	7.67	5.17-11.27	<0.001	3.20	2.34-4.40	<0.001
INSS stage
Stage 1
Stage 2	6.39	0.71-57.17	0.097	3.73	1.69-8.23	0.001
Stage 3	30.20	3.97-229.66	<0.001	7.63	3.59-16.24	<0.001
Stage 4	78.58	10.93-564.99	<0.001	12.49	6.33-24.66	<0.001
Stage 4S	9.63	1.07-86.19	0.043	3.42	1.44-8.11	0.005

OS: overall survival; EFS: event-free survival; HR: hazard ratio; CI: confidence interval.