Research Article
Identification and Validation of Inflammatory Response-Related Gene Signatures to Predict the Prognosis of Neuroblastoma
Table 4
Multivariate Cox regression analyses for identifying prognostic clinical characteristics.
| | Multivariate analysis (OS) | Multivariate analysis (EFS) | HR | 95% CI | value | HR | 95% CI | value |
| Risk score | 1.05 | 1.03-1.07 | <0.001 | 1.16 | 1.11-1.21 | <0.001 | Age | 1.0003 | 1.0002-1.0004 | <0.001 | 1.0002 | 1.0001-1.0003 | <0.001 | MYCN status | 2.84 | 1.87-4.31 | <0.001 | 1.26 | 0.87-1.81 | 0.216 | INSS stage | | | | | | | Stage 1 | | | | | | | Stage 2 | 6.99 | 0.78-62.78 | 0.082 | 3.76 | 1.70-8.31 | 0.001 | Stage 3 | 22.66 | 2.96-173.40 | 0.003 | 5.80 | 2.70-12.46 | <0.001 | Stage 4 | 39.19 | 5.40-284.22 | <0.001 | 7.66 | 3.82-15.37 | <0.001 | Stage 4S | 12.02 | 1.33-108.68 | 0.027 | 3.90 | 1.63-9.32 | 0.002 |
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OS: overall survival; EFS: event-free survival; HR: hazard ratio; CI: confidence interval.
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