Identification and Validation of Inflammatory Response-Related Gene Signatures to Predict the Prognosis of Neuroblastoma

Table 4

Multivariate Cox regression analyses for identifying prognostic clinical characteristics.

	Multivariate analysis (OS)			Multivariate analysis (EFS)
	HR	95% CI	value	HR	95% CI	value
Risk score	1.05	1.03-1.07	<0.001	1.16	1.11-1.21	<0.001
Age	1.0003	1.0002-1.0004	<0.001	1.0002	1.0001-1.0003	<0.001
MYCN status	2.84	1.87-4.31	<0.001	1.26	0.87-1.81	0.216
INSS stage
Stage 1
Stage 2	6.99	0.78-62.78	0.082	3.76	1.70-8.31	0.001
Stage 3	22.66	2.96-173.40	0.003	5.80	2.70-12.46	<0.001
Stage 4	39.19	5.40-284.22	<0.001	7.66	3.82-15.37	<0.001
Stage 4S	12.02	1.33-108.68	0.027	3.90	1.63-9.32	0.002

OS: overall survival; EFS: event-free survival; HR: hazard ratio; CI: confidence interval.