Expression and Prognostic Significance of PDIA3 in Cervical Cancer

Table 3

GO analysis of PDIA3 differentially co-expressed genes.

Category	Term	Count	-value	FDR
GOTERM_BP_DIRECT	GO:0006457~protein folding	7		0.00029
	GO:0034975~protein folding in endoplasmic reticulum	4		0.00029
	GO:0034976~response to endoplasmic reticulum stress	5		0.00157
	GO:0006890~retrograde vesicle-mediated transport, Golgi to ER	5		0.00167
	GO:0061077~chaperone-mediated protein folding	4	7	0.00307
	GO:0036500~ATF6-mediated unfolded protein response	3	0.00018	0.00495
	GO:0006621~protein retention in ER lumen	3	0.00018	0.00495
	GO:0015031~protein transport	7	0.00024	0.0058
	GO:0045454~cell redox homeostasis	4	0.0007	0.0151
	GO:0006465~signal peptide processing	3	0.00145	0.02823
	GO:0018279~protein N-linked glycosylation via asparagine	3	0.00368	0.06531
	GO:0006888~ER to Golgi vesicle-mediated transport	4	0.00561	0.09115
	GO:0051208~sequestering of calcium ion	2	0.00902	0.13533
	GO:0045047~protein targeting to ER	2	0.02019	0.28119
	GO:0006613~cotranslational protein targeting to membrane	2	0.02241	0.29129
GOTERM_CC_DIRECT	GO:0005783~endoplasmic reticulum	20
	GO:0005789~endoplasmic reticulum membrane	17
	GO:0034663~endoplasmic reticulum chaperone complex	6
	GO:0042470~melanosome	8
	GO:0005788~endoplasmic reticulum lumen	9
	GO:0005793~endoplasmic reticulum-Golgi intermediate compartment	6
	GO:0030133~transport vesicle	5		0.00072
	GO:0070062~extracellular exosome	17	0.00021	0.00203
	GO:0008250~oligosaccharyltransferase complex	3	0.00022	0.00203
	GO:0005790~smooth endoplasmic reticulum	3	0.00155	0.01287
	GO:0005925~focal adhesion	6	0.00176	0.01328
	GO:0031012~extracellular matrix	5	0.0043	0.02978
	GO:0016020~membrane	12	0.00779	0.04971
	GO:0033116~endoplasmic reticulum~Golgi intermediate compartment membrane	3	0.00912	0.05404
	GO:0005623~cell	3	0.02127	0.11771
	GO:0030126~COPI vesicle coat	2	0.03105	0.16066
	GO:0009986~cell surface	5	0.03291	0.16066
	GO:0071682~endocytic vesicle lumen	2	0.03541	0.16328
	GO:0000139~Golgi membrane	5	0.04306	0.17892
	GO:0005794~Golgi apparatus	6	0.04311	0.17892
GOTERM_MF_DIRECT	GO:0003756~protein disulfide isomerase activity	4	1.6E-05	0.00127
	GO:0051082~unfolded protein binding	5	0.00011	0.0043
	GO:0004579~dolichyl-diphosphooligosaccharide-protein glycotransferase activity	3	0.00018	0.00475
	GO:0044822~poly(A) RNA binding	10	0.00072	0.01461
	GO:0005046~KDEL sequence binding	2	0.0045	0.07285
	GO:0016757~transferase activity, transferring glycosyl groups	3	0.00831	0.11212
	GO:0046923~ER retention sequence binding	2	0.01121	0.12967
	GO:0051087~chaperone binding	3	0.0143	0.14474
	GO:0051787~misfolded protein binding	2	0.02669	0.2402
	GO:0005515~protein binding	27	0.03026	0.24513
	GO:0050750~low-density lipoprotein particle receptor binding	2	0.03543	0.2609
	GO:0016853~isomerase activity	2	0.04625	0.31219