Molecular Characterization and Clinical Characteristics of m5C-Based RNA Methylation in Spinal Cord Injury: Validated by qPCR

Figure 9

Protein–protein interaction (PPI) network and screening for hub genes. (a) PPI network of genes with differential 5-methylcytosine-based modification patterns in the Search Tool for the Retrieval of Interacting Genes/Proteins database. (b) Screening of 11 hub genes. (c) Heatmap showing correlation of hub genes. The upper-right half is the correlation in all samples. The lower-left half is the correlation in a spinal cord injury sample. The size and color of the nodes represent the size of the correlation. (d) Network diagram showing the correlation in expression of hub genes.

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