LncRNA BANCR Promotes Endometrial Stromal Cell Proliferation and Invasion in Endometriosis via the miR-15a-5p/TRIM59 Axis

Figure 2

LncRNA BANCR targets and inhibits miR-15a-5p. (a) Subcellular localization of lncRNA BANCR was predicted on the lncLocator database; (b) Subcellular localization of lncRNA BANCR was testified by the subcellular fractionation assay; (c) Binding sites of lncRNA BANCR to miR-15a-5p were predicted on the RNA22 database; (d) Binding relationship between lncRNA BANCR and miR-15a-5p was verified by the dual-luciferase assay; (e) miR-15a-5p expressions in eutopic and ectopic endometrial tissues () were determined by RT-qPCR; (f)—(g) miR-15a-5p expressions in Eut-ESCs and Ect-ESCs were determined by RT-qPCR; (h) Correlation between lncRNA BANCR and miR-15a-5p in ectopic endometrial tissues of EM patients () was analyzed using Pearson correlation analysis. Cell experiments were performed thrice independently. Data in figures (b), (d), (f), and (g) were formalized as mean ± SD. Data in figure (d) were analyzed using two-way ANOVA, data in figures (e)–(f) were analyzed using the t test, and data in figure (g) were analyzed using one-way ANOVA, followed by Tukey’s multiple comparison test. ** .

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