Early Breast Cancer Evolution by Autosomal Broad Copy Number Alterations

Figure 1

Frequency of all patients by genomic events. (a) Frequency of all patients (1,089 patients) gains (greater than 0 and green) and losses (less than 0 and red) for each SNP location on the Affymetrix SNP6.0 Microarray. (b) Frequency of all patients (984 patients) somatic mutations for any somatic mutation present in over 5% of all patients. (c) Frequency of the gains (greater than 0 and green) and losses (less than 0 and red) in patients, with 1 to 10 autosomal broad CNAs (180 patients), for each SNP location on the Affymetrix SNP6.0 Microarray. (d) Frequency of somatic mutations for any somatic mutation present in over 5% of patients in the subset in patients, with 1 to 10 autosomal broad CNAs (154 patients).

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