Research Article
HMOX1 Attenuates the Sensitivity of Hepatocellular Carcinoma Cells to Sorafenib via Modulating the Expression of ABC Transporters
Figure 9
Overexpression of HMOX1 upregulated the expression of ABCA6, ABCB1, ABCC1, and ABCG2 in sorafenib-resistant cells. (a) Relative mRNA expression of ABCA6 in Huh7-SR and HepG2-SR cells after being transfected with pcDNA3.1 or pcDNA3.1-HMOX1. (b) Relative mRNA expression of ABCB1 in Huh7-SR and HepG2-SR cells after being transfected with pcDNA3.1 or pcDNA3.1-HMOX1. (c) Relative mRNA expression of ABCC1 in Huh7-SR and HepG2-SR cells after being transfected with pcDNA3.1 or pcDNA3.1-HMOX1. (d) Relative mRNA expression of ABCG2 in Huh7-SR and HepG2-SR cells after being transfected with pcDNA3.1 or pcDNA3.1-HMOX1. . .
(a) |
(b) |
(c) |
(d) |