Unique Properties of Hepatocarcinogenesis-Resistant DRH Rat Hepatocytes Linked or Not Linked to the Drh1 Locus on Rat Chromosome 1
Proliferation of hepatocytes in Donryu, DRH, DRH.F344-Drh1, and F344 rats after LN treatment. (a) Day 2 after LN treatment. BrdU(+) hepatocyte nuclei occurred frequently in Donryu, DRH.F344-Drh1, and F344 livers but occurred much less frequently in DRH livers. (b) The BrdU LI in hepatocytes was most strongly increased on day 2 after LN treatment in Donryu, DRH.F344-Drh1, and F344 livers but was much lower in DRH livers. * in comparison with DRH () against Donryu (), DRH.F344-Drh1 (), or F344 ().
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