Unique Properties of Hepatocarcinogenesis-Resistant DRH Rat Hepatocytes Linked or Not Linked to the Drh1 Locus on Rat Chromosome 1
Figure 5
Liver injury after DEN and CCl4 treatment. (a) After DEN treatment, DRH.F344-Drh1 rats () exhibited high AST/ALT values, similar to those of Donryu () and F344 rats (); these levels were much higher than those of DRH rats (). *. (b) After CCl4 treatment, DRH.F344-Drh1 rats () also exhibited high AST/ALT values, similar to those of Donryu rats (); these levels were higher than those of DRH () and F344 rats (). *.
