International Journal of Hepatology / 2011 / Article / Tab 1

Research Article

Unique Properties of Hepatocarcinogenesis-Resistant DRH Rat Hepatocytes Linked or Not Linked to the Drh1 Locus on Rat Chromosome 1

Table 1

Comparison of hepatocytes from Donryu, DRH, DRH.F344-Drh1, and F344 rats.

DonryuDRHDRH.F344-Drh1 F344

Proliferation by LNHighLow*High*High
P38 dephosphorylationHighLow*High*High
Susceptibility to DEN and CCl4HighLow*High*High
Proliferation by GFHighLow**Low**High
Nuclear sizeLargeSmall**Small**Large

*Phenotype different between DRH and DRH.F344-Drh1. **Phenotype similar between DRH and DRH.F344-Drh1. High to DEN as Donryu, but lower to CCl4 than Donryu.

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