Correlation of Chimerism with Acute Graft-versus-Host Disease in Rats following Liver Transplantation
Figure 5
association of chimerism with aGVHD. PBMC chimerism following sex-mismatched liver transplantation was identified by real-time PCR based on a rat Y-chromosome-specific primer, as described in Materials and Methods (Section 2). As described in Materials and Methods (Section 2), group 3 received semiallogeneic liver transplantation together with the transfusion of splenocytes. Group 3 (aGVHD-), shown as white bars, consisted of 6 animals that were free from aGVHD, group 3 (aGVHD+) consisted of 6 animals with aGVHD following transplantation *, +.