Correlation of Chimerism with Acute Graft-versus-Host Disease in Rats following Liver Transplantation

Table 1

Lethality of aGVHD, survival time of each individual animal, and mean survival time (MST) for each group following liver transplantation. Each transplantation group consisted of 6 animals.

Transplantation group	Number of donor splenocytes transferred	Lethality of aGVHD (fraction of total)	Survival time in days (number of animals)	MST in days
Group 1
(L-L)	None	0	>100 (6)	>100
Group 2
(L-F1)	None	0	>100 (6)	>100
Group 3
(L-F1)	2×10^8	50% (3/6)	20	62.5
			24
			31
			>100 (3)
Group 4
(L-F1)	4×10^8	100% (6/6)	19	25.3
			21
			24
			26
			29
			33

Abbreviations: MST: mean survival time; L-L: transplantation from Lewis rat to Lewis rat; L-F1: transplantation from Lewis rat to (LewisxBN)F1 rat.