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International Journal of Hepatology
Volume 2011, Article ID 968161, 15 pages
Research Article

Hepatitis C Virus E2 Protein Ectodomain Is Essential for Assembly of Infectious Virions

1Department of Molecular Immunology, Novartis Vaccines and Diagnostic, Via Fiorentina 1, 53100 Siena, Italy
2Division of Immunoregulation, National Institute of Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK
3Department of Pathology, Stanford University, Stanford, CA 94305, USA
4Department of Structural and Functional Biology, University of Naples “Federico II” at MSA, 80132 Naples, Italy

Received 14 July 2010; Accepted 5 September 2010

Academic Editor: Claus Hellerbrand

Copyright © 2011 Alessia Bianchi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [3 citations]

The following is the list of published articles that have cited the current article.

  • Rui Li, Yan Qin, Ying He, Wanyin Tao, Nan Zhang, Cheguo Tsai, Paul Zhou, and Jin Zhong, “Production of Hepatitis C Virus Lacking the Envelope-Encoding Genes for Single-Cycle Infection by Providing Homologous Envelope Proteins or Vesicular Stomatitis Virus Glycoproteins in trans,” Journal Of Virology, vol. 85, no. 5, pp. 2138–2147, 2011. View at Publisher · View at Google Scholar
  • Thomas H R Carlsen, Troels K H Scheel, Santseharay Ramirez, Steven K H Foung, and Jens Bukh, “Characterization of hepatitis C virus recombinants with chimeric E1/E2 envelope proteins and identification of single amino acids in the E2 stem region important for entry.,” Journal of virology, vol. 87, no. 3, pp. 1385–99, 2013. View at Publisher · View at Google Scholar
  • Min Hyeok Jee, Sung Key Jang, Ji Hoon Park, Oh Sung Kwon, and Sun Ju Keum, “Infectivity of hepatitis C virus correlates with the amount of envelope protein E2: Development of a new aptamer-based assay system suitable for measuring the infectious titer of HCV,” Virology, vol. 439, no. 1, pp. 13–22, 2013. View at Publisher · View at Google Scholar