International Journal of Hepatology / 2012 / Article / Tab 5

Review Article

Fungal Infections: Their Diagnosis and Treatment in Transplant Recipients

Table 5

Pharmacokinetic parameters of the major echinocandins in clinical use*.

Agent 𝐢 m a x 𝑑 1 / 2 𝑉 𝑑 AUC 𝐢 𝑑 FeUFeS

Anidulafungin2.07–3.5250.544–530.26<1%30%, <10% unchanged

*Dose 50 mg single dose, 𝐢 m a x : maximum concentration, 𝑑 1 / 2 : elimination half-life, 𝑉 𝑑 : volume of distribution, AUC: area under the plasma concentration and time curve, 𝐢 𝑑 : total clearance, FeU: fraction excreted in urine, FeS: fraction excreted in stool.

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.