2D MR Spectroscopy Combined with Prior-Knowledge Fitting Is Sensitive to HCV-Associated Cerebral Metabolic Abnormalities

Table 1

Metabolite changes between healthy controls and HCV+ patients calculated from the 2D L-COSY data.

Metabolites/Cr	Healthy controls (mean ± SD) n = 14	HCV+ patients (mean ± SD) n = 14
tNAA	1.405 ± 0.153	1.303 ± 0.253
tCh	0.291 ± 0.092	0.331 ± 0.126
Glu+Gln	1.838 ± 0.310	1.780 ± 0.582
mI^†	1.056 ± 0.237	1.311 ± 0.264
Scy	0.089 ± 0.049	0.094 ± 0.035
GSH^†	0.140 ± 0.040	0.243 ± 0.090
Glu	1.585 ± 0.447	1.631 ± 0.546
GABA	0.371 ± 0.226	0.331 ± 0.137
Asp	0.398 ± 0.070	0.417 ± 0.080
GPC	0.166 ± 0.074	0.176 ± 0.047

^†𝑃 value < 0.05.