International Journal of Hepatology / 2012 / Article / Tab 3

Review Article

Pathological Features of New Animal Models for Primary Biliary Cirrhosis

Table 3

Novel PBC animal models reported since 2006.

Spontaneous models
(1) NOD.c3c4 mice [2325]
(2) Dominant negative TGF-β receptor II mice [2631]
(3) IL-2 receptor α −/− mice [32, 33]
(4) Scurfy mice [34]
(5) Ae2a,b −/− mice [35]

Xenobiotic-immunized induced model
(1) 6-Bromohexanoate-immunized guinea pigs [36]
(2) 2-Octynoic acid-immunized mice [3740]

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