Potential Antioxidant Role of Tridham in Managing Oxidative Stress against Aflatoxin-B₁-Induced Experimental Hepatocellular Carcinoma

Table 1

Effect of TD on indicators of macromolecular damage in liver of control and experimental animals.

Parameters	Group I (control)	Group II (AFB1 induced)	Group III (AFB1 induced + TD)	Group IV (TD alone)
Lipid peroxides (LPO)	51.64±5.62	79.41±9.26^a∗	53.15±6.14^b∗	50.44±5.02^cNS
Thiobarbituric acid reactive substances (TBARSs)	3.89±0.41	7.74±0.73^a∗	4.25±0.49^b∗	3.93±0.38^cNS
Protein carbonyls (PCOs)	6.13±0.57	14.75±1.78^a∗	8.31±0.89^b∗	5.96±0.64^cNS

Units. LPO: nmoles of MDA formed/mg protein, TBARS: nmoles/100 g tissue, protein carbonyl: nmoles of DNPH formed/min/mg protein. Values are expressed as mean ± SD for six animals. Comparisons are made between “a” Group II versus Group I, “b” Group III versus Group II, “c” Group IV versus Group I. The symbol *represents the statistical significance at 𝑃<0.05. NS: nonsignificant.