Potential Antioxidant Role of Tridham in Managing Oxidative Stress against Aflatoxin-B₁-Induced Experimental Hepatocellular Carcinoma

Table 5

Effect of TD on nonenzymic antioxidants and thiols in kidney of control and experimental animals.

Parameters	Group I (control)	Group II (AFB1 induced)	Group III (AFB1 induced + TD)	Group IV (TD alone)
Vitamin C	2.94±0.38	1.52±0.22^a∗	2.78±0.35^b∗	2.95±0.37^cNS
Vitamin E	2.85±0.29	1.12±0.17^a∗	2.42±0.27^b∗	2.91±0.31^cNS
Total thiols (TSH)	7.17±1.14	2.88±0.33^a∗	6.85±0.78^b∗	7.79±0.81^cNS
Non protein thiols (NPSH)	4.75±0.61	2.68±0.34^a∗	4.31±0.51^b∗	4.68±0.56^cNS
Reduced glutathione (GSH)	27.04±2.97	13.54±2.21^a∗	25.51±2.98^b∗	27.98±3.23^cNS

Units-GSH-mg/100 g tissue, Vitamin C and E-mg/g wet tissue, TSH and NPSH: μg/mg protein. Values are expressed as mean ± SD for six animals. Comparisons are made between “a” Group II versus Group I, “b” Group III versus Group II, “c” Group IV versus Group I. The symbol *represents the statistical significance at 𝑃<0.05. NS: nonsignificant.