A Crucial Role of Bone Morphogenetic Protein Signaling in the Wound Healing Response in Acute Liver Injury Induced by Carbon Tetrachloride
Figure 5
Proliferative activity in the CCl4-injured liver of BMPR1A-KO mice. (a) Immunohistochemistry for Ki-67, a cell cycle marker, in the CCl4-injured liver. mice were infected with mock or Ad-Cre for 14 days, and mice were infected with Ad-Cre as a control. Brown nuclei indicate Ki-67-positive cells. Scale bars: 25 μm. (b) Quantitative analysis of Ki-67-positive cells. Ki-67-positive cells were counted in 10 randomly taken microscopic photos, and are shown as percentages relative to the total cell number. All data are shown as the means ± SE from three independent experiments. *, significant difference by Student’s -test.
