Review Article

Acute Liver Failure Caused by Amanita phalloides Poisoning

Table 2

Clinical phases of the Amatoxin syndrome.

PhasesOnset from ingestionSymptoms and signs

Stage 1. Lag phase0–24 hAsymptomatic
Stage 2. Gastrointestinal phase6–24 hNausea, vomiting, crampy abdominal pain, and severe secretory diarrhea
Stage 3. Apparent convalescence24–72 hAsymptomatic, worsening of hepatic and renal function indices
Stage 4. Acute liver failure4–9 daysHepatic and renal failure → multiorgan failure → death