IRS1 Expression in Hepatic Tissue and Leukocytes in Chronic Hepatitis C Virus Infected Patients: A Comparative Study

Table 1

Glycemic and lipid profiles of patients with chronic hepatitis C and its correlation with viral load and fibrosis.

Variable	General	F0/F1	F2/F3	𝑃	VL <p400000 UI/mL	VL >400000 UI/mL	𝑃
BMI	24.95	24.46	25.57	0.296	23.79	25.03	0.270
(mean ± SD)	(±2.77)	(±2.64)	(±2.86)		(±2.18)	(±2.75)
Blood Glucose	96.34	94.42	99.64	0.162	88.50	99	0.001
(mean ± SD)	(±11.05)	(±10.64)	(±11.34)		(±4.47)	(±11.72)
Insulin	9.76	8.16	13.64	0.043	7.68	11.50	0.117
(median 25th–75th%)	(5.83–14.76)	(4.96–12.05)	(7.53–17.03)		(4.74–10.24)	(6.32–16.40)
HOMA-IR	2.25	1.94	3.51	0.054	1.68	2.76	0.216
(median 25th–75th%)	(1.40–3.78)	(1.17–3.00)	(1.70–4.62)		(1.01–2.44)	(1.50–4.09)
Total cholesterol	169.28	174.89	161.08	0.211	160	169.38	0.576
(mean ± SD)	(±33.29)	(±38.68)	(±22.29)		(±57.60)	(±27.68)
HDL cholesterol	52.53	54.21	50.08	0.388	51.33	53.43	0.705
(mean ± SD)	(±13.06)	(±9.60)	(±17.07)		(±9.37)	(±12.35)
Triglycerides	99	108	96.50	0.855	89	99	0.226
(median 25–75th%)	(70–123)	(69–125.5)	(78.50–129)		(56–108)	(70–123)
Adiponectin	7.89	6.85	11.86	0.393	9.76	7.89	0.893
(median 25–75th%)	(3.85–17)	(3.03–16.87)	(4.92–17.02)		(3.22–15.61)	(3.23–19.48)

BMI: body mass index; VL: viral load; F0/F1: minimal/mild fibrosis; F2/F3: significant fibrosis.