IRS1 Expression in Hepatic Tissue and Leukocytes in Chronic Hepatitis C Virus Infected Patients: A Comparative Study

Table 2

IRS1 in leukocytes and liver of patients with hepatitis C virus and their correlation.

Variable	IRS1 leukocytes			IRS1 liver
	(𝑛=31)			(𝑛=36)
	Value	Spearman (rho)	𝑃	Value	Spearman (rho)	𝑃
Age	44.77	−0.368	0.02	44.89	−0.297	0.07
(mean ± SD)	(±8.4)			(±7.9)
HOMA-IR	2.63	−0.118	0.55	2.13	−0.341	0.04
(median 25th–75th%)	(1.38–3.86)			(1.28–3.90)
HCV viral load	1119,225	0.291	0.16	807,000	−0.135	0.44
(median 25th–75th%)	(518,280–3107,865)			(310,000–3101,797)
Fibrosis	F3—2 (6.9%)	−0.022	0.91	F3—3 (8.1%)	−0.182	0.28
(𝑛/%)	F1,2—27 (93.1%)			F1,2—34 (91.9%)
Fibrosis progression	0,0006876	−0.030	0.87	0,0006876	−0.187	0.28
(median 25th–75th%)	(0.0005–0.00100)			(0.0005–0.00100)