Pretreatment of Small-for-Size Grafts In Vivo by γ-Aminobutyric Acid Receptor Regulation against Oxidative Stress-Induced Injury in Rat Split Orthotopic Liver Transplantation

Figure 2

Biochemical and coagulation profiles. (a) AST levels. There were significant differences between laparotomy and SOLT with saline (𝑃<0.05*) and between SOLT with saline and SOLT with GABAR agonist (𝑃<0.05^†). (b) ALT levels. There were significant differences between laparotomy and SOLT with saline (𝑃<0.05*) and between SOLT with saline and SOLT with GABAR agonist (𝑃<0.05^†). (c) T-Bil levels. There were significant differences between laparotomy and SOLT with saline (𝑃<0.05*) and between SOLT with saline and SOLT with GABAR agonist (𝑃<0.05^†). (d) PT-INR. There were significant differences between laparotomy and SOLT with saline (𝑃<0.05*) and between SOLT with saline and SOLT with GABAR agonist (𝑃<0.05†). AST, aspartate aminotransferase; ALT, alanine aminotransferase; GABAR, γ-aminobutyric acid receptor; SFSG, small-for-size graft; SOLT, split orthotopic liver transplantation; PT-INR, international normalized ratio of prothrombin time; and T-Bil, total bilirubin.

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