International Journal of Hepatology / 2013 / Article / Tab 2

Review Article

Changing Epidemiology of Hepatocellular Adenoma in the United States: Review of the Literature

Table 2

Published series of hepatocellular adenoma in the United States (1973–1985).

Author
Year of publication
Study duration
Sample populationHormonal therapy (%)Women (%)Mean ageSingleMultiplePresenting symptomsHemorrhageMalignancyTreatment

Mays and Christopherson [18]
1984
(1973–1984)
71Single-center surgical registry83%100%30NRNR(36.6%) mass
(31%) hemoperitoneum
(24%) pain
(5.6%) incidental
(2.8%) unknown
NRNR
Weil et al. [19]
1979
(1970–1978)
8Single-center surgical series4 (50%)7 (88%)248 (100%)06 fever
6 abdominal pain
3 palpable abdominal mass
4 (50%)0Resection
Bourne Rooks
et al. [20]
1979
(1957–1976)
79Database of pathology referrals73 (92%)79 (100%)30.4NRNR34% intraperitoneal bleeding
15% intratumoral hemorrhage
47% abdominal mass
19% abdominal pain
49%0Resection
Edmondson et al. [21]
1976
(1955–1976)
42Single-center surgical series31/361 (86%)42 (100%)NRNRNR12 (28%) pain
18 (43%) palpable mass
2 (4.7%) incidental
10 (24%)041 resection
Ameriks et al. [22]
1975
(1969–1973)
8Single-center surgical series8 (100%)8 (100%)33.6713 hemoperitoneum
3 abdominal pain, intrahepatic hemorrhage
3 palpable mass
6 (75%)0Resection
Baum et al. [23]
1973
7Case series7 (100%)7 (100%)28.7705 abdominal pain
2 right upper quadrant mass
50Resection

NR: not reported.
1Data on OCP use not available in 6 cases.