Clinical Features of Adult Patients with Acute Hepatitis B Virus Infection Progressing to Chronic Infection

Table 1

Clinical data of the subjects according to HBV genotypes.

	Group A	Group B
Number of patients	3	22	N.S.
Male : female	1 : 2	13 : 9	N.S.
Age	28 (20–84)	35 (18–81)	N.S.
Apparent acute hepatitis	1 (33%)	22 (100%)	< 0.05
Fulminant hepatitis	0	3 (13.6%)	N.S.
T. bil >3.0 mg/dL	0	20 (90.9%)	< 0.01
T. bil (mg/dL), max	1.00 ± 0.36	8.43 ± 5.14	< 0.05
ALT >500 IU/L	0	22 (100%)	< 0.01
ALT (IU/L), max	250 ± 211	2733 ± 1540	< 0.01
HBeAg (positive)	3 (100%)	10 (45.5%)	N.S.
HBV-DNA >7 LC/mL	3 (100%)	1 (4.5%)	< 0.01
Genotype; A : B : C : D	0 : 0 : 2 : 1	3 : 1 : 14 : 1; (undetermined 3)	N.S.

N.S.: not significant; T. bil: total bilirubin; ALT: alanine aminotransferase; LC: log copies; HBeAg: hepatitis B e antigen; HBV: hepatitis B virus.