Research Article
Clinical Features of Adult Patients with Acute Hepatitis B Virus Infection Progressing to Chronic Infection
Table 1
Clinical data of the subjects according to HBV genotypes.
| | Group A | Group B | |
| Number of patients | 3 | 22 | N.S. | Male : female | 1 : 2 | 13 : 9 | N.S. | Age | 28 (20–84) | 35 (18–81) |
N.S. | Apparent acute hepatitis | 1 (33%) | 22 (100%) | < 0.05 | Fulminant hepatitis | 0 | 3 (13.6%) | N.S. | T. bil >3.0 mg/dL | 0 | 20 (90.9%) | < 0.01 | T. bil (mg/dL), max | 1.00 ± 0.36 | 8.43 ± 5.14 | < 0.05 | ALT >500 IU/L | 0 | 22 (100%) | < 0.01 | ALT (IU/L), max | 250 ± 211 | 2733 ± 1540 | < 0.01 | HBeAg (positive) | 3 (100%) | 10 (45.5%) | N.S. | HBV-DNA >7 LC/mL | 3 (100%) | 1 (4.5%) | < 0.01 | Genotype A : B : C : D | 0 : 0 : 2 : 1 | 3 : 1 : 14 : 1 (undetermined 3) | N.S. |
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N.S.: not significant; T. bil: total bilirubin; ALT: alanine aminotransferase; LC: log copies; HBeAg: hepatitis B e antigen; HBV: hepatitis B virus.
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