Table 2: Clinical and biochemical characteristics of 209 subjects with NAFLD divided by serum cytokeratin-18 tertiles.

Cytokeratin-18 tertiles
I II III

Males (%)68.163.062.7ns
Age (yrs) ns
Body mass index (kg/m2) <0.001
Urinary 8-iso-PGF2α (pg/mg creatinine) <0.001
HOMA-IR2.8 (1.9/4.0)3.2 (2.4/5.7)5.3 (3.4/7.3)<0.001
Total cholesterol (mg/dL) ns
HDL (mg/dL)50 (43/61)47 (38/54)43 (39/51)<0.05
Triglycerides (mg/dL)125.5 (85.5/160.3)138 (102.0/180.5)165.0 (125.0/206.0)<0.01
-GT (IU/L)23 (16.8/36.5)27 (17.5/44.0)30 (18/53)ns
ALT (IU/L)31 (22.8/40)28 (20/41.5)26 (20/40)ns
AST (IU/L)22 (18/28)21 (17/26.5)21 (17/28)ns
Adiponectin (ng/mL)12 (10.4/14.1) 7.5 (5.5/10.5)5 (4/7)<0.001
sNOX2-dp (pg/mL)49 (40/58.3)60 (50/66)67 (64/71)<0.001
Hamaguchi score <0.01
Metabolic syndrome (%)49.469.084.8<0.001
Diabetes (%)20.330.143.3<0.05