Review Article
What Are the Precursor and Early Lesions of Peripheral Intrahepatic Cholangiocarcinoma?
Table 2
Occurrence of biliary epithelial lesions related to cholangiocarcinoma.
| | Peripheral ICC | Perihilar CC | HCC | cHC-CC | | | | | |
| Biliary fibroadenoma | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | Bile duct adenoma | 0 (0%) | 0 (0%) | 1 (4%) | 1 (5%) | Von Meyenburg complex | 9 (24.3%) | 6 (17.6%) | 7 (28.0%) | 6 (33.3%) | Bile duct adenoma-like lesion | 12 (32.4%) | 4 (11.8%) | 3 (12%) | 6 (33.3%) | Atypical small bile duct lesion | 4 (10.8%) | 0 (0%) | 0 (0%) | 1 (5.6%) | Biliary epithelial neoplasm (BilIN) 2/3 | | | | | Perihilar bile duct | 6 (16.2%) | 18 (52.9%) | 1 (4%) | 2 (11.1%) | Peribiliary glands | 4 (10.8%) | 17 (50.0%) | 0 (0%) | 1 (5.6%) |
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CC: cholangiocarcinoma; ICC: intrahepatic CC; HCC: hepatocellular carcinoma; cHC-CC: combined hepatocellular cholangiocarcinoma.
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