The Value of Serum Midkine Level in Diagnosis of Hepatocellular Carcinoma

Table 1

Comparison between each of the two studied groups regarding serums AFP and MDK.

Parameters	MDK (ng/mL)		Significance		AFP (ng/mL)		Significance
	Median	1st and 3rd quartile			Median	1st and 3rd quartile
HCC ( = 40) versus LC ( = 30)	0.625; 0.15	0.45–0.96; 0.12–0.23	6.278	0; (HS)	39.3; 17.5	13.5–225.5; 10–36	2.223	0.026; (S)
HCC ( = 40) versus healthy (30)	0.625; 0.125	0.45–0.96; 0.1–0.15	7.085	0; (HS)	39.3; 1	13.5–225.5; 0.5–2	6.914	0; (HS)
LC ( = 30) versus healthy (30)	0.15; 0.125	0.12–0.23; 0.1–0.15	1.559	0.118; (NS)	17.5; 1	10–36; 0.5–2	6.290	0; (HS)

MDK: midkine, AFP: alpha fetoprotein, HCC: hepatocellular carcinoma, and LC: liver cirrhosis.