The Value of Serum Midkine Level in Diagnosis of Hepatocellular Carcinoma

Table 3

Comparison between MDK at cutoff value 0.387 ng/mL and AFP at cutoff values 88.5, 20, and 200 ng/mL regarding sensitivity and specificity in diagnosis of HCC.

	Cutoff	Sensitivity		Specificity
		%		%
Midkine versus; AFP	0.387; 88.5	92.5; 40	0.001; HS	83.3; 96.7	0.195; NS
Midkine versus; AFP	0.387; 20	92.5; 62.5	0.001; HS	83.3; 53.3%	0.012; S
Midkine versus; AFP	0.387; 200	92.5; 25.0%	0.001; HS	83.3; 100	0.052; NS

MDK: midkine; AFP: alpha-fetoprotein.
Chi-square test.
Fisher’s exact test.