Serum Adiponectin, Vitamin D, and Alpha-Fetoprotein in Children with Chronic Hepatitis C: Can They Predict Treatment Response?
Table 1
Baseline demographic, laboratory, and histopathological characteristics of the hepatitis C virus-infected group.
Item
All ()
Responders ()
Nonresponders ()
value
Age (years)
11.46 ± 3.48 (4–18)
11.8 ± 3.6 (4–18)
10.6 ± 3.1 (5–16)
0.237
Sex (male)
33 (66%)
25 (69.4%)
8 (57.1%)
0.41
BMI
18.56 ± 2.79 (14.21–25.36)
18.8 ± 2.9 (14.2–25.4)
17.98 ± 2.4 (14.8–21.1)
0.334
Hemoglobin (g/dL)
11.7 ± 0.76 (10–13.2)
11.6 ± 0.75 (10–13.1)
11.9 ± 0.75 (10.3–13.2)
0.209
White blood cells (×103/L)
7.3 ± 1.8 (4.5–12.3)
7.3 ± 1.6 (4.5–11.8)
7.3 ± 2.2 (4.8–12.3)
0.892
Neutrophils (×103/L)
5.14 ± 1.2 (3.24–8.14)
5.1 ± 1.13 (3.24–8.14)
5.2 ± 1.4 (3.3–7.6)
0.828
Platelets (×103/L)
242 ± 82 (122–431)
238 ± 84 (122–431)
253 ± 76 (123–351)
0.544
ALT (U/L)
56.4 ± 13.6 (40–108)
56.3 ± 12.3 (40–86)
56.6 ± 17.1 (40–108)
0.943
AST (U/L)
62.9 ± 25.7 (35–157)
63 ± 28.1 (35–157)
61.9 ± 19.4 (40–110)
0.665
Stage of fibrosis
0.23
Absent/minimal
29 (58%)
19 (52.8%)
10 (71.4%)
Significant
21 (42%)
17 (47.2%)
4 (28.6%)
Grade of activity
0.345
Minimal
7 (14%)
4 (11.1%)
3 (21.4%)
Mild
43 (86%)
32 (88.9%)
11 (78.6%)
HCV: hepatitis C virus; BMI: body mass index; ALT: alanine transaminase, AST: aspartate transaminase. value is for the comparison between responders and nonresponders.
