Review Article

Elbasvir/Grazoprevir: A Review of the Latest Agent in the Fight against Hepatitis C

Table 1

SVR12 rates of first-line therapies for the treatment of HCV genotypes 1a, 1b, and 4 [13, 2832].

SVR12 in treatment-naïve patients
OverallGenotype 1aGenotype 1bGenotype 4

Grazoprevir-elbasvir [13]95%92%99%100%
Ledipasvir-sofosbuvir [28] 100%NANANA
Paritaprevir-ritonavir-ombitasvir + dasabuvir [29] 91.8%92.2%100%NA
Simeprevir + sofosbuvir [30, 31] 93%NANANA
Daclatasvir + sofosbuvir [32] 100%NANANA

NA: not applicable.