The Effect of Artichoke Leaf Extract on Alanine Aminotransferase and Aspartate Aminotransferase in the Patients with Nonalcoholic Steatohepatitis

Table 1

Changes in study biomarkers in intervention and placebo groups.

Marker	Intervention group			Placebo group			Intergroup difference
	Before	After	value	Before	After	value
Weight (kg)	83.90 ± 15.83	79.28 ± 14.25	<0.001	81.81 ± 14.25	77.05 ± 14.83	<0.001	0.859
ALT (mg/dL)	81.77 ± 38.73	38.40 ± 14.15	<0.001	74.13 ± 23.61	64.07 ± 20.36	<0.001	<0.001
AST (mg/dL)	45.53 ± 13.78	24.60 ± 7.43	<0.001	44.50 ± 9.82	39.60 ± 10.41	<0.001	<0.001
FBS (mg/dL)	108.07 ± 28.90	97.60 ± 14.50	0.029	107.43 ± 18.48	102.57 ± 10.78	0.096	0.302
Chol (mg/dL)	206.47 ± 31.20	182.87 ± 34.64	0.001	213.67 ± 48.48	211.63 ± 48.96	0.686	0.008
LDL (mg/dL)	122.14 ± 30.42	108.12 ± 32.36	0.039	116.09 ± 29.38	113.23 ± 31.79	0.659	0.120
HDL (mg/dL)	45.87 ± 10.46	43.33 ± 8.20	0.129	45.50 ± 7.50	44.87 ± 6.10	0.689	0.403
TG (mg/dL)	193.37 ± 86.03	154.50 ± 84.93	0.011	179.87 ± 45.67	184.23 ± 57.83	0.659	0.016
SBP (mg/dL)	132.70 ± 13.55	126.57 ± 8.54	0.004	130.23 ± 10.34	128.20 ± 6.62	0.044	0.070
DBP (mg/dL)	80.00 ± 9.21	79.03 ± 6.89	0.578	80.87 ± 8.52	81.63 ± 7.31	0.504	0.403