Clinical Study

The Effect of Artichoke Leaf Extract on Alanine Aminotransferase and Aspartate Aminotransferase in the Patients with Nonalcoholic Steatohepatitis

Table 2

Multivariate linear regression models for determining the role of Cynara scolymus use on changes in liver enzymes and lipid profile.

Marker VariableBeta95% confidence interval value

ALT changeArtichoke use−31.365−45.201 to −17.528<0.001
Male sex−0.634−16.252 to 14.9830.935
Age−0.754−1.434 to −0.0740.030

AST changeArtichoke use−16.041−21.405 to −10.677<0.001
Male sex−2.995−9.049 to 3.0600.326
Age0.003−0.261 to 0.2660.983

Chol changeArtichoke use−21.673−37.245 to −6.1010.007
Male sex−17.072−34.648 to 0.5050.057
Age0.041−0.723 to 0.8060.914

TG changeArtichoke use−41.960−76.613 to −7.3070.019
Male sex−28.315−67.428 to 10.7980.153
Age−0.496−2.198 to 1.2060.562