Cardiovascular Autonomic Dysfunction in Patients of Nonalcoholic Fatty Liver Disease

Table 2

Time domain and frequency domain indices of HRV in the study population.

	Controls	NAFLD without diabetes	NAFLD with diabetes	value
Time domain indices
SDNN (ms)	40.7	30.2		0.006
	(24.6–61.5)	(15.5–47.8)	(17.59–28.2)
SDSD (ms)	24.2	25.9		0.009
	(17.3–43.2)	(8.8–36.8)	(9.36–19.6)
pNN50 (%)	0.04	0.04		0.008
	(0.00–0.22)	(0.00–0.16)	(0.00–0.01)
Frequency domain indices
LF nu	40.2	41.9	37.8	0.855
	(33.4–53.6)	(27.1–52.3)	(23.9–53.2)
HF nu	29.2	26.8	19.7	0.575
	(18.4–43.9)	(15.6–36.3)	(15.5–38.9)
LF : HF ratio	1.5	1.6	1.6	0.843
	(1.0–2.6)	(1.0–2.2)	(0.9–2.9)
Total power (ms^2)	1166.5	658.4		0.005
	(383.5–2312.6)	(202.9–1379.2)	(173.3–545.4)

Values are expressed as median (IQR); versus control; versus NAFLD without diabetes.
SDNN: standard deviation of all NN intervals; SDSD: standard deviation of differences between adjacent NN intervals; pNN50%: NN50 count divided by the total number of all NN intervals; LF: low frequency (0.04–0.15 Hz); HF: high frequency (0.15–0.40 Hz); nu: normalized unit.