Research Article

Cardiovascular Autonomic Dysfunction in Patients of Nonalcoholic Fatty Liver Disease

Table 3

Time domain and frequency domain indices of HRV in controls, Grade I and Grade II NAFLD.

Controls ()Grade I ()Grade II () value

Diabetics (, %)16, 51.6%8, 44.4%0.62
Time domain indices
SDNN (ms)40.728.30.010
(24.6–61.5)(19.5–46.3)(14.7–26.0)
SDSD (ms)24.218.80.026
(17.3–43.2)(12.4–29.8)(9.1–28.4)
pNN50 (%)0.040.010.016
(0.00–0.22)(0.00–0.07)(0.00–0.01)
Frequency domain indices
LF nu40.237.844.50.435
(33.4–53.6)(27.1–53.3)(20.1–50.0)
HF nu29.219.723.10.650
(18.4–43.9)(14.9–37.9)(19.3–35.8)
LF : HF ratio1.51.61.40.804
(0.9–3.0)(0.9–3.4)(0.8–2.7)
Total power (ms2)1166.5515.00.006
(383.5–2312.6)(271.1–1374.3)(157.5–382.6)

Values are expressed as median (IQR); versus control.
SDNN: standard deviation of all NN intervals; SDSD: standard deviation of differences between adjacent NN intervals; pNN50%: NN50 count divided by the total number of all NN intervals; LF: low frequency (0.04–0.15 Hz); HF: high frequency (0.15–0.40 Hz); nu: normalized unit.