Research Article

Preoperative Neutrophil-to-Lymphocyte Ratio Plus Platelet-to-Lymphocyte Ratio Predicts the Outcomes after Curative Resection for Hepatocellular Carcinoma

Table 1

Clinicopathological characteristics of patients undergoing curative hepatectomy for HCC.

Clinical variablesOverall (n=132) (%)

Patient factors
Male (n, %)116 (87.9%)
Age (years; mean ± SD)65.2 ± 10.2
Hepatitis B (n, %)75 (56.8%)
Child-Pugh Class B (n, %)13 (9.8%)

Laboratory data
ICG>15 (n, %)30 (22.7%)
Creatinine (mean ± SD)98±91

Surgical factors
Major hepatectomy (n, %)61 (46.2%)
Operation time >350min (n, %)43 (32.6%)
EBL >500ml (n, %)81 (61.4%)

Tumor factors
AFP >400ug/L (n, %)18 (13.6%)
Tumor size >5cm (n, %)60 (45.4%)
Multiple tumors (n, %)30 (22.7%)
R1 resection (n, %)13 (9.8%)

Postoperative factors
Wound infection6 (4.5%)
Pneumonia22 (16.7%)
UTI7 (5.3%)
Bile leak2 (1.5%)
Intra-abdominal collection4 (3.0%)
Liver failure11 (8.3%)

Follow-up
30-day mortality3 (2.3%)
LOS (days, mean ± SD)14.0 ± 19.2
OS (months, median [IQR])24(1-88)
RFS (months, median [IQR])17(1-84)

ICG: indocyanine green; EBL: estimated blood loss; AFP: a-fetoprotein; UTI: urinary tract infection; LOS: length of stay; OS: overall survival; RFS: recurrence free survival; IQR: interquartile range; SD: standard derivation.