Research Article

The High Prevalence of Negative Hepatitis B Surface Antibody (Anti-HBs) among Pregnant Women in Bandung, Indonesia: A Community-Based Study

Table 1

Participant characteristics and HBsAg status.

All participantsHBsAg positiveHBsAg negativeOR (95% CI)

Overall, (%)196 (100)12 (6.1)184(93.9)
Age
 Mean year (SD)27.7 (6.1)27.1 (5.2)27.7 (6.2)
 Distribution, (%)
  13–2010 (5.1)1 (0.5)9 (4.6)1
  20–2451 (26.0)2 (1.0)49 (25.0)2.722 (0.223-33.27)0.433
  25–2959 (30.1)5 (2.6)54 (27.6)1.200 (0.125-11.50)0.874
  30–3444 (22.4)3 (1.5)41 (20.9)1.519 (0.141-16.32)0.730
  >3532 (16.3)1 (0.5)31 (15.8)3.444 (0.195-60.71)0.398
Bodyweight
 Mean kg (SD)53.6 (9.7)56.3 (8.9)53.4 (9.8)
Height
 Median cm (IQR)155.0 (6.0)158.0 (9.0)155.0 (6.0)
BMI
 Mean kg/m2 (SD)22.3 (3.9)23.1 (3.7)22.3 (3.9)
 Distribution, (%)
  <18.530 (15.3)5 (2.6)25 (12.8)1
  18.5–24.9121 (61.8)4 (2.0)117 (59.7)5.850 (1.466-23.34)0.012§
  25–29.934 (17.3)3 (1.5)31 (15.8)2.067 (0.450-9.499)0.351
  ≥3011 (5.6)0 (0)11 (5.6)N/A
Maternal employment, (%)
 Unemployed143 (73.0)10 (5.1)133 (67.9)1
 Fulltime26 (13.3)1 (0.5)25 (12.8)1.880 (0.230-15.34)0.556
 Part time27 (13.8)1 (0.5)26 (13.3)1.955 (0.240-15.93)0.531
Spouse employment, (%)
 Unemployed5 (2.6)0 (0)5 (2.6)N/A
 Fulltime91 (46.4)6 (3.1)85 (43.4)1
 Part time100 (51.0)6 (3.1)94 (48.0)1.106 (0.344-3.560)0.866
Family income (monthly), (%)
 <250 USD120 (61.2)8 (4.1)112 (57.1)1
 250–499 USD59 (30.2)4 (2.0)55 (28.1)0.982 (0.283-3.404)0.977
 500–999 USD14 (7.1)0 (0)14 (7.1)N/A
 >1000 USD3 (1.5)0 (0)3 (1.5)N/A
Education, (%)
 Preschool1 (0.5)0 (0)1 (0.5)N/A
 Elementary school8 (4.1)1 (0.5)7 (3.6)1
 Intermediate school23 (11.7)3 (1.5)20 (10.2)0.952 (0.085-10.72)0.968
 High school98 (50.0)5 (2.6)93 (47.4)2.657 (0.272-25.98)0.401
 Graduate64 (32.7)3 (1.5)61 (31.1)2.905 (0.265-31.84)0.383
 Postgraduate2 (1.0)0 (0)2 (1.0)N/A
HBV vaccine frequency history, (%)
 Unknown85 (43.4)5 (2.6)80 (40.8)1
 None108 (55.1)7 (3.6)101 (51.5)0.902 (0.276-2.948)0.864
 1-32 (1.0)0 (0)2 (1.0)N/A
 41 (0.5)0 (0)1 (0.5)N/A
TT vaccine frequency history, (%)
 None85 (43.4)5 (2.6)80 (40.8)1
 1-292 (46.9)6 (3.1)86 (43.9)0.788 (0.218-2.840)0.715
 ≥319 (9.7)1 (0.5)18 (9.2)0.563(0.059-5.363)0.617
Gravidae, (%)
 172 (36.7)5 (2.6)67 (34.2)1
 2-3100 (51.0)7 (3.6)93 (47.4)0.991 (0.302-3.259)0.989
 ≥424 (12.2)0 (0)24 (12.2)N/A
Parturien, (%)
 077 (39.2)5 (2.6)72 (36.7)1
 1-2103 (52.6)7 (3.6)96 (49.0)0.952 (0.290-3.123)0.936
 ≥316 (8.2)0 (0)16 (8.2)N/A
Abortus, (%)
 0165 (84.2)11 (5.6)154 (78.6)1
 1-230 (15.3)1 (0.5)29 (14.8)2.071 (0.257–16.67)0.494
 ≥31 (0.5)0 (0)1 (0.5)N/A
Insurance, (%)
BPJS53 (27.0)2 (1.0)133 (67.9)1
None143 (73.0)10 (5.1)51 (26.0)1.917 (0.406-9.052)0.411
Maternal ethnicity, (%)
 Sundanese184 (93.9)12 (6.1)172 (87.8)N/A
 Javanese8 (4.1)0 (0)8 (4.1)
 Batak1 (0.5)0 (0)1 (0.5)
 Malay1 (0.5)0 (0)1 (0.5)
 Others2 (1.0)0 (0)2 (1.0)
Possible route of HBV infection, yes answered, (%)
 Ever had hepatitis history0 (0)0 (0)0 (0)N/A
 Ever had surgery6 (3.1)0 (0)6 (3.1)
 Mother’s tattoo2 (1.0)0 (0)2 (1.0)
 Spouse’s tattoo3 (1.5)0 (0)3 (1.5)
 Ever had a blood transfusion2 (1.0)0 (0)2 (1.0)
 Spouse’s blood transfusion history0 (0)0 (0)0 (0)
 Hepatitis history from a spouse1 (0.5)0 (0)1 (0.5)
 Hepatitis history from family1 (0.5)0 (0)1 (0.5)
 Mother history of IDU0 (0)0 (0)0 (0)
 Spouse history of IDU0 (0)0 (0)0 (0)

§Significant value. Cumulative income rounded and converted from Indonesia Rupiah (IDR) to US Dollar (USD), BPJS = Indonesian National Insurance, Mother (first ascend) or siblings. OR: odds ratio; CI: confidence interval, N/A: not applicable; TT: tetanus toxoid; IDU: injecting drug user.