The Influence of Donor and Recipient Complement C3 Polymorphisms on Liver Transplant Outcome
Table 5
Life tables for freedom from acute rejection. Acute rejection life table up to 2500 days posttransplantation in liver graft donors and recipients classified according to C3 genotype or presence of C3F allele.
C3 subgroup
% rejection-free
()
30 d
90 d
180 d
1 yr
5 yr
2500 d
FF/FF (0)
—
—
—
—
—
—
FF/FS (3)
67%
67%
67%
67%
67%
67%
FF/SS (16)
94%
94%
94%
94%
94%
94%
FS/FF (5)
100%
100%
100%
100%
100%
100%
FS/FS (56)
80%
77%
77%
73%
73%
73%
FS/SS (116)
78%
75%
73%
73%
72%
72%
SS/FF (16)
88%
81%
81%
81%
81%
81%
SS/FS (81)
91%
89%
86%
84%
81%
81%
SS/SS (184)
78%
77%
76%
72%
69%
69%
0.10
0.15
0.23
0.22
0.17
0.17
Donor FF (20)
90%
90%
90%
90%
90%
90%
Donor FS (182)
80%
77%
75%
74%
73%
73%
Donor SS (290)
82%
81%
79%
76%
73%
73%
0.27
0.41
0.28
0.32
0.28
0.28
Recipient FF (21)
90%
86%
86%
86%
86%
86%
Recipient FS (143)
87%
84%
82%
80%
77%
77%
Recipient SS (324)
79%
77%
76%
74%
71%
71%
value
0.18
0.14
0.19
0.21
0.14
0.14
values were derived by Mantel-Cox log-rank or Wilcoxon rank analysis.
