Research Article
Clinical Characteristics of Patients with Hepatocellular Carcinoma: A Single-Center 3-Year Experience from Somalia
Table 1
Comparison of hepatocellular carcinoma (HCC) patients by portal vein thrombosis (PVT+/-) (
), Jan 2017–Dec 2019, Somalia.
| | PVT (-)
() | PVT (+)
() | |
| | Gender (%) | | | | | Male | 163 (82.7) | 34 (17.3) | 0.210 | | Female | 63 (90) | 7 (10) | | Age (median)(years) | 40 (22-76) | 55 (18-100) | 0.009 | | AFP | 2000 (201-2000) | 2000 (203-2000) | 0.014 | | AST (U/L) | 97 (0-4483) | 216 (0-16335) | 0.001 | | ALT (U/L) | 39 (0-1269) | 77 (0-3456) | 0.001 | | Creatinine (mg/dl) | 0.6 (0-5.1) | 0.7 (0-8.4) | 0.206 | | Direct_Bilirubin (μmol/L) | 0.2 (0-93) | 1.2 (0-28.43) | 0.001 | | Protrombin time (seconds) | 0 (0-61.9) | 0 (0-59.5) | 0.230 | | Total_Bilirubin (μmol/L) | 0.55 (0-30) | 3.3 (0-34.87) | <0.001 | | Albumin (g/L) | 2.85 (0-5.1) | 2.7 (0-4.4) | 0.836 | | GGT (U/L) | 0 (0-987) | 36 (0-876) | 0.202 | | ALP (U/L) | 0 (0-1325) | 178 (0-1750) | 0.023 | | Hb (g/dl) | 7 (0-15) | 8 (0-13) | 0.637 | | Platelet (×109/L) | 70 (0-996) | 72.5 (0-876) | 0.657 | | WBC×103 | 9 (0-987) | 13 (0-86) | 0.270 | | CRP | 54 (0-987) | 65 (0-865) | 0.355 | | Tumor size (cm) | 4 (0-27) | 8 (0-30) | 0.010 | | Child-Pugh | | | | | A | 175 (89.3) | 21 (10.7) | 0.001 | | B | 33 (71.7) | 13 (28.3) | | C | 17 (70.8) | 7 (29.2) | | Cirrhosis (-) (%) | 163 (86.7) | 25 (13.3) | 0.195 | | Cirrhosis (+) (%) | 62 (79.5) | 16 (20.5) | | Number of nodules | | | | | Unifocal | 34 (79.1) | 9 (20.9) | 0.703 | | Multifocal | 33 (73.3) | 12 (26.7) | | Tumor distribution | | | | | Unilobular | 199 (85.4) | 34 (14.6) | 0.515 | | Bilobular | 27 (79.4) | 7 (20.6) | | Maximal tumor size (cm) | | | | | <5 cm | 111 (89.5) | 13 (10.5) | 0.087 | | 5-10 | 32 (84.2) | 6 (15.8) | | >10 | 83 (79) | 22 (21) |
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Abbreviations: ALT: alanine aminotransferase; AST: aspartate aminotransferase; PT: prothrombin time; GGT: gamma glutamyl transpeptidase; INR: international normalized ratio; PT: prothrombin time; AFP: alpha fetoprotein; WBCs: white blood cells; CRP: C-reactive protein; normal values: ALT (5–45 U/L), AST (5–40 U/L), alkaline phosphatase (38–155 U/L), albumin (2.5–6.0 g/dL), total serum bilirubin (0.1–1.3 mg/dL), and serum direct bilirubin (0.0–8.4 mg/dL).
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