Research Article
Clinical Characteristics of Patients with Hepatocellular Carcinoma: A Single-Center 3-Year Experience from Somalia
Table 2
Comparison of hepatocellular carcinoma (HCC) patients by maximal tumor diameter categories (
), Jan 2017–Dec 2019, Somalia.
| | MTD | | <5 cm
() | 5-10 cm
() | ≥10 cm
() | |
| | Gender, N (%) | | | | | | Male | 86 (43.7) | 28 (14.2) | 83 (42.1) | 0.242 | | Female | 38 (54.3) | 10 (14.3) | 22 (31.4) | | Age (median)(years) | 52 (18-100) | 55 (20-91) | 53 (20-90) | 0.696 | | AFP | 1046.14 (201-2000) | 2000 (203-2000) | 2000 (223-2000) | <0.001 | | AST (U/L) | 95 (0-16335) | 97 (0-4483) | 120 (0-3432) | 0.175 | | ALT (U/L) | 40.5 (0-3456) | 41.5 (0-1260) | 42 (0-477) | 0.750 | | Creatinine (mg/dl) | 0.6 (0-8.4) | 0.8 (0-2.5) | 0.7 (0-7.8) | 0.334 | | Direct bilirubin (μmol/L) | 0.25 (0-93) | 0.1 (0-17.7) | 0.3 (0-22.7) | 0.784 | | PT (seconds) | 0 (0-59.5) | 0 (0-48.6) | 0 (0-61.9) | 0.652 | | Total bilirubin (μmol/L) | 0.6 (0-34.87) | 0.45 (0-22.94) | 0.9 (0-29.4) | 0.333 | | Albumin (g/dL) | 2.7 (0-4.7) | 3.15 (0-5) | 2.8 (0-5.1) | 0.259 | | GGT (U/L) | 0 (0-987) | 0 (0-321) | 17 (0-768) | 0.290 | | ALP (U/L) | 0 (0-1750) | 0 (0-743) | 113 (0-1157) | 0.186 | | Hb (g/dl) | 8 (0-15) | 7 (0-14) | 7 (0-13) | 0.575 | | Platelet (×109/L) | 67 (0-996) | 85 (0-980) | 67 (0-876) | 0.204 | | WBC×103 | 12 (0-987) | 8 (0-97) | 9 (0-90) | 0.709 | | CRP | 58 (0-876) | 65 (0-987) | 56 (0-879) | 0.741 | | Child-Pugh | | | | | | A | 90 (45.9) | 28 (14.3) | 78 (39.8) | 0.014 | | B | 16 (34.8) | 10 (21.7) | 20 (43.5) | | C | 18 (75) | 0 (0) | 6 (25) | | Cirrhosis (-) (%) | 94 (50) | 23 (12.2) | 71 (37.8) | 0.153 | | Cirrhosis (+) (%) | 30 (38.5) | 15 (19.2) | 33 (42.3) | | PVT (-) | 111 (49.1) | 32 (14.2) | 83 (36.7) | 0.091 | | PVT (+) | 13 (31.7) | 6 (14.6) | 22 (53.7) | | Number of nodules | | | | | | Unifocal | 27 (62.8) | 5 (11.6) | 11 (25.6) | 0.006 | | Multifocal | 13 (28.9) | 7 (15.6) | 25 (55.6) | | Tumor distribution | | | | | | Unilobular | 116 (49.8) | 29 (12.4) | 88 (37.8) | 0.007 | | Bilobular | 8 (23.5) | 9 (26.5) | 17 (50) |
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Abbreviations: ALT: alanine aminotransferase; AST: aspartate aminotransferase; PT: prothrombin time; GGT: gamma glutamyl transpeptidase; INR: international normalized ratio; :PT: prothrombin time; AFP: alpha fetoprotein; WBCs: white blood cells; CRP: C-reactive protein; PVT: portal vein thrombosis; normal values: ALT (5–45 U/L), AST (5–40 U/L), alkaline phosphatase (38–155 U/L), albumin (2.5–6.0 g/dL), total serum bilirubin (0.1–1.3 mg/dL), and serum direct bilirubin (0.0–8.4 mg/dL).
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