Urinary BA Indices as Prognostic Biomarkers for Complications Associated with Liver Diseases

Table 3

Univariate logistic regression analyses for the prediction of developing ascites in the entire liver-patient population based on BA indices.

BA (μM)/BA indices	B-value (regression coefficient)	value	Odds ratio (OR): Exp ()
			1 unit change	10% change	20% change
Total BA	0.002	0.059	1.002	1.010	1.020
Total LCA	0.024	0.275	1.024	1.007	1.013
Total UDCA	0.001	0.538	1.001	1.002	1.004
Total CDCA	0.009	0.002	1.009	1.017	1.034
Total DCA	-0.001	0.871	0.999	0.999	0.999
Total HDCA	-20.099	1.000	0.001	0.980	0.961
Total MDCA	-20.104	0.999	0.001	0.923	0.851
Total CA	0.052	0.007	1.053	1.013	1.027
Total MCA	0.008	0.528	1.008	1.002	1.005
Total HCA	0.407	0.012	1.502	1.007	1.015
% LCA	-0.071	0.004	0.931	0.936	0.877
% UDCA	-0.049	0.001	0.952	0.892	0.795
% CDCA	0.048	0.001	1.049	1.178	1.387
% DCA	-0.061	0.001	0.941	0.908	0.825
% HDCA	-6.66	0.108	0.001	0.980	0.960
% MDCA	-3.281	0.003	0.038	0.880	0.774
% CA	0.065	0.005	1.067	1.040	1.081
% MCA	-0.007	0.713	0.993	0.996	0.991
% HCA	-0.671	0.001	0.511	0.977	0.954
Total Unamidated	0.016	0.076	1.016	1.009	1.017
Total G-amidated	0.002	0.103	1.002	1.008	1.017
Total T-amidated	0.019	0.016	1.019	1.011	1.021
% Amidation	0.041	0.017	1.042	1.433	2.054
% G-amidation	-0.004	0.665	0.996	0.970	0.940
% T-amidation	0.037	0.002	1.038	1.039	1.080
Total Unsulfated	0.061	0.076	1.016	1.009	1.017
Total sulfated	0.002	0.061	1.002	1.009	1.018
% Sulfation	0.012	0.338	1.012	1.106	1.224
Total mono-OH	0.024	0.275	1.024	1.007	1.013
Total Di-OH	0.002	0.074	1.002	1.008	1.017
Total tri-OH	0.018	0.029	1.018	1.010	1.021
% mono-OH	-0.071	0.004	0.931	0.936	0.877
% Di-OH	0.018	0.095	1.018	1.142	1.304
% tri-OH	0.021	0.108	1.021	1.027	1.055
Total 12α-OH	0.008	0.162	1.008	1.007	1.014
Total non-12α-OH	0.002	0.068	1.002	1.008	1.017
12α-OH/non12α-OH	-0.787	0.114	0.455	0.974	0.948
CA/CDCA	-0.997	0.159	0.369	0.974	0.949
% 12α-OH	-0.033	0.014	0.968	0.928	0.861
% non-12α-OH	0.033	0.014	1.034	1.291	1.666
Total primary	0.007	0.003	1.007	1.017	1.034
Total secondary	0.001	0.543	1.001	1.003	1.005
Primary/secondary	0.09	0.001	1.094	1.020	1.041
% primary	0.049	0.001	1.050	1.258	1.582
% secondary	-0.049	0.001	0.952	0.770	0.594
HI	0.074	0.012	1.077	0.999	0.998

BA concentrations are in (μM), while BA indices are in percentage.