Host Factors in the Natural History of Chronic Hepatitis B: Role of Genetic Determinants

Table 3

The differences of proportion between SNPs of IL10-592 A/C based on natural history of chronic hepatitis B (CHB).

Dependent variables	OR	95% CI	value
IT and IC to LR
AA vs. AC	1.567	0.797–3.106	0.200
AA vs. CC	0.779	0.236–2.415	0.798
AA+AC vs. CC	0.654	0.204–1.953	0.462
AA vs. AC+CC	1.345	0.720–2.524	0.372
IT and IC to ENH
AA vs. AC	1.257	0.604–2.617	0.604
AA vs. CC	0.388	0.065–1.600	0.240
AA+AC vs. CC	0.356	0.061–1.423	0.157
AA vs. AC+CC	1.012	0.510–2.004	1
LR to ENH
AA vs. AC	0.803	0.389–1.643	0.612
AA vs. CC	0.498	0.078–2.367	0.503
AA+AC vs. CC	0.544	0.087–2.503	0.516
AA vs. AC+CC	0.753	0.376–1.496	0.418

IT: immune tolerant; IC: immune clearance; LR: low replicative; ENH: HBeAg-negative immune reactivation; OR: odds ratio; CI: confidence interval. , , and .